What is Hemoglobin?
Anemia

What is Hemoglobin?

Written by

Lauren Dobischok
29 March, 2022

Medically checked article All HOMED-IQ content is reviewed by medical specialists

Hemoglobin (Hb) is part of the red blood cells in our body. It is important to maintain a healthy hemoglobin level to feel our best and ensure our body can function properly. When our hemoglobin value is too high or too low, physical complaints can arise.


Table of Contents


What is Hemoglobin?

Hemoglobin is a protein that allows for the absorption and transport of oxygen and carbon dioxide in red blood cells. The red blood cells in our body ensure the delivery of oxygen from the lungs to our body’s cells. Oxygen allows your muscles and organs to obtain energy from the food you eat, also known as cellular respiration. After the oxygen is released to the cells, hemoglobin is then able to absorb carbon dioxide which ends up in the lungs. The carbon dioxide then leaves the body through exhalation (Sanquin).

Why is hemoglobin important?

Hemoglobin is essential for maintaining healthy oxygen levels in your body. A hemoglobin deficiency can lead to anemia, a condition where the blood cannot carry enough oxygen to tissues. Conversely, excessively high hemoglobin levels may be a sign of dehydration, chronic lung disease, or other underlying conditions, and can increase the risk of blood clots or stroke.

Because hemoglobin reflects how well your body transports oxygen, it is a key marker in many health checks and blood tests, including complete blood counts (CBCs) and at-home blood tests.

What is an optimal hemoglobin value?

Normal hemoglobin levels vary based on age, sex, and other factors such as pregnancy. They can be expressed in mmol/L (millimoles per liter) or g/dL (grams per deciliter), depending on the country or lab. Here’s a general overview:

GroupNormal Range (g/dL)

Normal Range (mmol/L)

Adult males13,8 – 17,2 g/dL8,5 – 11 mmol/L
Adult females12,1 – 16,1 g/dL7,5 – 10 mmol/L
Children > 6 years10,5 – 16,1 g/dL6,5 – 10 mmol/L
Children 1 month – 6 years9,7 – 14,5 g/dL6 – 9 mmol/L

Source: Dutch Association of Hematology

Values slightly outside these ranges may not indicate a health problem, but persistently high or low values should be evaluated by a healthcare professional.

Causes and symptoms of low hemoglobin

A low hemoglobin level is often a sign of anemia. There are several types of anemia, each with different causes:

  • Iron-deficiency anemia – due to poor iron intake or blood loss (e.g. menstruation, ulcers)
  • Vitamin deficiency anemia – caused by low levels of vitamin B12 or folate
  • Chronic disease anemia – linked to long-term illnesses like kidney disease
  • Aplastic anemia – when the body stops producing enough red blood cells
  • Hemolytic anemia – when red blood cells are destroyed too quickly
  • Inherited disorders – such as sickle cell anemia or thalassemia

Common symptoms of low hemoglobin include:

  • Fatigue
  • Weakness
  • Shortness of breath
  • Dizziness or light-headedness
  • Cold hands and feet
  • Headache
  • Pale or yellowish skin

Source: Máxima MC, 2022

Causes and symptoms high hemoglobin

While less common, high hemoglobin levels can occur due to:

  • Smoking – reduces oxygen availability, prompting the body to make more red blood cells
  • Living at high altitudes – where less oxygen is available
  • Lung diseases – such as COPD or pulmonary fibrosis
  • Dehydration – which concentrates blood components
  • Bone marrow disorders – like polycythemia vera
  • Performance-enhancing drugs – such as erythropoietin (EPO)

Symptoms of high hemoglobin may include:

  • Headache
  • Blurred vision
  • Red or flushed skin
  • High blood pressure
  • Dizziness
  • Nosebleeds

Extremely high hemoglobin can increase the risk of blood clots, strokes, or heart attacks.

Would you like to get an overview for yourself?

With the Active Vitamin B12 (Holo-TC) Test and the Folic Acid Test from Homed-IQ, you can check from the comfort of your own home whether you have a deficiency of these important nutrients.

How do I increase my hemoglobin level?

When you have low hemoglobin, it is important to consume more iron. There is iron in all kinds of foods, such as meat, fish, chicken, legumes, and vegetables such as spinach. It is also possible to use an iron supplement. It is advisable to check your hemoglobin level a few months after making dietary changes to see if any improvements have been made. Contact your GP if you require more advice on how to increase your hemoglobin level.

Summary

Hemoglobin is a vital protein that ensures your body gets the oxygen it needs. Both low and high levels can point to underlying health issues, so understanding your numbers is key. While symptoms of abnormal hemoglobin can vary, regular testing and a healthy lifestyle can help keep your levels in check.

References

Bloedarmoede – Máxima MC. (2017, September 27). Interne Geneeskunde. https://www.mmc.nl/internegeneeskunde/aandoeningen-en-behandelingen/bloedarmoede/?_ga=2.252499337.1416331597.1669584503-555177933.1667906179

Isala. (2021, November). Hematologische aandoening (PID): H2 Optionele bijlage Myeloproliferatieve aandoeningen. https://www.isala.nl/patientenfolders/6551-hematologische-aandoening-pid-h2-optionele-bijlage-myeloproliferatieve-aandoeningen/?_ga=2.152885433.1416331597.1669584503-555177933.1667906179

Nederlandse Internisten Vereniging. (2020, January 30). Normaalwaarden ». https://hematologienederland.nl/patientinfo/diagnose-en-behandeling/normaalwaarden/?_ga=2.152885433.1416331597.1669584503-555177933.1667906179

Wat is hemoglobine en welke waarde is normaal? | Sanquin . (n.d.). https://www.sanquin.nl/. https://www.sanquin.nl/over-bloed/eiwitten/hemoglobine?gclid=CjwKCAiA9tyQBhAIEiwA6tdCrFiDOf8-HC_ZusmDi4mgn-M8LMrAeJTEQjFZNKA6m88-2BvbsODVIBoC7hEQAvD_BwE

About the author

Lauren Dobischok

Lauren is a health scientist and science communicator currently living in the Netherlands. Originally from Canada, she completed a Research Master’s in Health Sciences at the Netherlands Institute of Health Sciences at Erasmus University Rotterdam (NIHES) with a specialisation in epidemiology. Prior to her master’s degree, she completed a Bachelor’s degree in Health Sciences at Simon Fraser University. With a background in public health, her goal is to create accurate scientific content that is easy to understand and empowers people to make informed decisions. Within Homed-IQ, Lauren works as a Product Developer and Content Lead, working closely with physicians and scientists on medical devices for Homed-IQ’s new products and written communications.