Chlamydien oder Harnwegsinfektion
STIs

Chlamydia vs UTI: How to tell the difference

Written by

Lauren Dobischok
16 September, 2025

Medically checked article All HOMED-IQ content is reviewed by medical specialists

Chlamydia and urinary tract infections (UTIs) are common but distinct infections. They often share similar symptoms such as burning during urination and lower abdominal pain and affect the urinary and genital tracts, which is why they are often confused. However, a clear diagnosis and timely detection are extremely important, as the causes, transmission routes, and treatment approaches differ. Untreated or incorrectly treated infections can lead to long-term health problems. In this blog, you will learn everything about the differences between chlamydia and a urinary tract infection.


Table of Contents


What is a chlamydia infection?

A chlamydia infection is a sexually transmitted infection (STI) caused by the bacterium Chlamydia trachomatis. It is one of the most common STIs and often goes unnoticed because it is asymptomatic in many cases. Around 70% of infected women and 50% of infected men show no or only mild symptoms. Untreated chlamydia infections can have serious health consequences, such as chronic inflammation of the reproductive organs, infertility, or complications during childbirth in pregnant women (Cleveland Clinic, 2023).

What is a urinary tract infection (UTI)?

A urinary tract infection (UTI) is a bacterial infection of the urinary tract, most commonly caused by bacteria such as Escherichia coli. The abbreviation UTI stands for urinary tract infection. It typically affects the lower urinary tract—the urethra and bladder—and is then referred to as cystitis. Less commonly, it can also affect the upper urinary tract, such as the kidneys, which is known as pyelonephritis. UTIs are not sexually transmitted but can be triggered by sexual activity. If left untreated, they can lead to serious infections, especially when the kidneys are involved (CDC, 2024).

Differences between chlamydia and urinary tract infection (UTI)

CharacteristicChlamydiaUrinary tract infection (UTI)
Transmission / originSexually transmitted (unprotected intercourse; vaginal, anal, or oral)

Transmission at birth from mother to newborn
Bacteria (mainly E. coli) from the intestines enter the urethra and multiplyr

Risk factors include poor intimate hygiene, frequent sex, low fluid intake, weak immune system; higher risk in women due to shorter urethra
Complications (long-term damage)Infertility, premature birth, inflammation of the uterus and fallopian tubesKidney infection (pyelonephritis), fever, sepsis (in severe cases)
DiagnosisUrinproben oder Abstriche von Schleimhäuten (z. B. Gebärmutterhals, Harnröhre, Rachen)

Bei: Hausarzt, Gynäkologen oder Urologen oder durch Selbsttests für zu Hause
Urine test with dipsticks for signs of inflammation; urine culture
TreatmentAntibiotics prescribed by a doctor (take regularly and complete the course); all sexual partners should be treated; no intercourse during therapyMild cases: lots of fluids, symptom relief.

Severe or recurrent cases: antibiotics for several days, painkillers, lots of fluids

Sources: Cleveland Clinic, 2023; NHS, 2022; NHS, 2022

Can a UTI be triggered by sexual activity?

Yes, a urinary tract infection (UTI) can be triggered or facilitated by sexual activity. Intercourse can introduce bacteria, usually from the intestines, into the urethra, where they can cause an infection.

Symptoms: chlamydia vs. urinary tract infection (UTI)

Chlamydia infections often occur without noticeable symptoms, while urinary tract infections (UTIs) usually present with clear, noticeable signs. Typical symptoms of both conditions compared:

Chlamydia infectionUrinary tract infection (UTI)
– Unusual, often purulent or clear discharge from the urethra or vagina.
– Pain or burning sensation when urinating.
– Lower abdominal pain or feeling of pressure.
– Pain or burning sensation during sexual intercourse.
– In men: pain and swelling in the testicle area, which may indicate epididymitis.
– Strong, frequent or urgent urination, often in small amounts.
Burning and pain when urinating.
– Cloudy, foul-smelling or bloody urine.
– Pain in the lower abdomen or pelvic region.
– In advanced infections: fever, chills and flank pain (indicating kidney involvement).

Sources: Mayo Clinic, 2024; Cleveland Clinic, 2023

When should you see a doctor?

  • If you have UTI-specific symptoms such as intense burning or pain during urination and changes in urine.
  • If UTI symptoms do not improve after one to two days despite adequate fluid intake.
  • If you have chlamydia-specific symptoms such as unusual discharge.
  • After unprotected sex with changing partners, especially if chlamydia is suspected.
  • If you experience persistent discomfort in the lower abdomen or pelvic region.
  • Because chlamydia often causes no symptoms, regular STI screenings are recommended.

Early medical consultation is important to ensure the correct diagnosis and treatment and to prevent complications (Mayo Clinic, 2024; Cleveland Clinic, 2023).

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Tips for effective prevention of chlamydia and urinary tract infection (UTI)

To prevent urinary tract infections (UTIs), the following measures can help:

  • Drink plenty of fluids: Drinking lots of water helps flush the urinary tract regularly.
  • Hygiene: Wipe from front to back after using the toilet to keep intestinal bacteria away.
  • Urinate after sexual intercourse: This helps flush out any bacteria that may have entered.
  • Intimate hygiene: Use mild products, as harsh soaps can disrupt the natural balance.
  • Breathable underwear: Cotton underwear helps maintain a dry environment and reduces bacterial growth.

Source: NHS, 2022

Chlamydia infections can be prevented with the following measures:

  • Use condoms: Condoms offer reliable protection by reducing direct mucous membrane contact—though only when used correctly.
  • Regular screening tests: STI tests are advisable with frequent partner changes, in a new relationship, or after unprotected sex. Testing is also important because chlamydia often causes no symptoms and can only be detected and treated in time this way.
  • Open communication: Honest conversations about sexual health build trust and help prevent the unintentional transmission of infections.

Source: Cleveland Clinic, 2023

Summary

Chlamydia and urinary tract infections (UTIs) are common but distinct infections that often share similar symptoms, such as burning during urination and lower abdominal pain. While chlamydia is often asymptomatic and sexually transmitted, UTIs usually result from bacteria in the urinary tract and cause clearly noticeable symptoms. However, the causes and treatment approaches differ, which is why a clear diagnosis is essential to avoid long-term health consequences.

References

Cleveland Clinic. (n.d.). Chlamydia: Causes, symptoms, treatment & prevention. Retrieved November 5, 2024, from https://my.clevelandclinic.org/health/diseases/4023-chlamydia

Mayo Clinic. (2024, September 12). Chlamydia trachomatis – Symptoms and causes. Retrieved November 5, 2024, from https://www.mayoclinic.org/diseases-conditions/chlamydia/symptoms-causes/syc-20355349

NHS. (n.d.). Chlamydia – Treatment. Retrieved November 5, 2024, from https://www.nhs.uk/conditions/chlamydia/treatment/

National Institute of Diabetes and Digestive and Kidney Diseases. (n.d.). Treatment for bladder infection in adults. Retrieved November 5, 2024, from https://www.niddk.nih.gov/health-information/urologic-diseases/bladder-infection-uti-in-adults/treatment

Centers for Disease Control and Prevention. (2024, January 22). Urinary tract infection basics. Retrieved November 5, 2024, from https://www.cdc.gov/uti/about/index.html

NHS. (n.d.). Urinary tract infections (UTIs). Retrieved November 5, 2024, from https://www.nhs.uk/conditions/urinary-tract-infections-utis/

Cleveland Clinic. (n.d.). Urinary tract infection (UTI): Causes, symptoms & treatment. Retrieved November 5, 2024, from https://my.clevelandclinic.org/health/diseases/9135-urinary-tract-infections

About the author

Lauren Dobischok

Lauren is a health scientist and science communicator currently living in the Netherlands. Originally from Canada, she completed a Research Master’s in Health Sciences at the Netherlands Institute of Health Sciences at Erasmus University Rotterdam (NIHES) with a specialisation in epidemiology. Prior to her master’s degree, she completed a Bachelor’s degree in Health Sciences at Simon Fraser University. With a background in public health, her goal is to create accurate scientific content that is easy to understand and empowers people to make informed decisions. Within Homed-IQ, Lauren works as a Product Developer and Content Lead, working closely with physicians and scientists on medical devices for Homed-IQ’s new products and written communications.